CONTRIBUTOR(S): Vetstream Ltd, Julie Hamilton-Elliott,
Your cat has been prescribed mexiletine to improve their heart rhythm.
Your veterinarian has prescribed mexiletine to control an abnormal heart rhythm.
Mexiletine tablets are given orally two to three times per day and may be administered with or without food.
Possible side-effects include nausea, vomiting, lethargy/depression, convulsions, tremor, abnormal eye movements (nystagmus), slow heart rate, low blood pressure, jaundice and hepatitis. Any side-effects of mexiletine should be reported to your veterinarian. Your pet may be able to continue with the drug if side-effects are mild, but it’s best to let your veterinarian know as soon as possible, so that they can decide whether additional medications or different medications are required. Mexiletine may interact with other drugs, including atropine, opioids, cimetidine, acetazolamide, phenytoin, methionine and rifampicin. Low potassium levels in the blood can reduce the effect of mexiletine.
Mexiletine should be administered according to your veterinarian’s instructions.
Dispose of any unused mexiletine safely – do not flush down the toilet or sink. Ask your veterinary team if they take back medication for disposal. Do not give mexiletine to other pets.
If you miss a dose, give the next dose as soon as possible. If you give too much mexiletine contact your veterinarian as overdose can result in abnormal heart rhythms which may require treatment.
If your pet is unwell, contact your veterinarian for advice.
Mexiletine should only be given to the cat that it has been prescribed for. If accidentally given to other pets, contact your veterinarian for advice. If accidentally consumed by a human, speak to your primary care physician or poison control center. Bring the tablets with you when you visit a physician.
Your veterinarian will need to examine your pet periodically to be able to prescribe this medication safely and within prescribing regulations. Repeat ECGs may be required to assess ongoing response.