Diarrhea

In adult rabbits, diarrhea is quite uncommon. It is important to check your rabbit daily for diarrhea as it could be due to a rapidly-progressing disease that requires early treatment or could lead to other problems such as flystrike.

Diarrhea is the production of abnormally loose stools. When a rabbit has diarrhea, it will not only become dehydrated due to fluid loss, but will also lose other important substances such as electrolytes (salts like potassium and chloride) and nutrients, including vitamins.

Clinical signs of diarrhea include dirty fur around your rabbit’s bottom, which may lead to secondary skin problems, as well as weight loss, lethargy and a reduced appetite. The stools may be soft, semi-fluid or watery, and may contain mucus or blood in some conditions, and the rabbit may have a painful abdomen.

Pain in rabbits can be difficult to determine, since as a prey species they are programmed to hide signs of discomfort. Signs of abdominal pain may include bruxism (teeth grinding), pressing their abdomen on the ground or a hunched posture.

General treatment involves rehydrating the rabbit and re-establishing a healthy gut microbial environment. Nursing also includes care to prevent secondary skin problems.

Rabbits normally produce two types of stool, hard pellets and soft ‘cecotrophs’. These soft stools look like a small bunch of grapes and contain essential nutrients that the rabbit needs to eat every day. They are usually produced at night and eaten directly from the anus, so owners don’t see them. If your rabbit doesn’t eat their caecotrophs, it can be due to several reasons:

• A sore back making it painful to be down.
• Dental pain.
• Inappropriate diet.
• Excessive weight, particularly around the dewlap or hindquarters.

If the rabbit doesn’t eat their cecotrophs, you may see them collecting at the anus, sticking to the rabbit’s fur and causing ‘clagging’.

Cecotrophs are produced one to three times daily. They are soft but formed and covered in a layer of clear mucus. Hard pellets are also produced in normal rabbits. Kits don’t produce cecotrophs until weaning age at 3-6 weeks old.

Conversely, diarrhea occurs throughout the day, and stools are unformed and foul-smelling. The rabbit is usually depressed and off its food.

Some agents cause diarrhea on their own, but many only cause problems in rabbits with other conditions, including other infections, digestive upset due to a low-fibre/high-carbohydrate diet, or with general poor health affecting the rabbit’s immune system.

Bacterial causes of diarrhea are more common in young rabbits, eg Salmonella, Escherichia coli (E.coli) and Clostridium piliforme (Tyzzer’s disease).

Some species of coccidian parasites (pathogenic Eimeria spp) can cause diarrhoea around and after weaning.

Viruses, such as retroviruses and coronaviruses, may cause mild diarrhea on their won or more serious diarrhoea with bacterial co-infections.

Identification of the cause may require fecal tests to be performed, and often general treatment is started before laboratory results are available.

Besides the supportive treatment outlined above, specific antimicrobial medications may be required to treat these infections.

Adult rabbits have microbes in their gut to help digest food. Before weaning, kits have almost no microbes along their digestive tract. At weaning, the rabbit’s digestive tract changes significantly and it is particularly susceptible to infections around this time.

Antibiotics can affect the healthy microbes in the rabbit’s digestive system. Some antibiotics, especially those in the macrolide and lincosamide groups, alter the balance of microbes and allow overgrowth of organisms that can cause disease, eg clostridial bacteria. Giving certain antibiotics by mouth is more likely to affect the gut microbes than giving them by injection. Rabbits on a poor diet, which is low in fiber, and more susceptible to the adverse effects of antibiotics.

Milder cases of antibiotic-induced diarrhea may have altered stools and reduced appetite, but in severe cases the altered microbes can lead to a generalised toxic state in the rabbit which may be fatal.

Flies like to lay their eggs in moist warm areas. If your rabbit has diarrhea on its skin and in its fur, flies will attack this area, especially in warm weather. When the fly eggs hatch, the maggots will feed on material nearby. In some cases, the maggots enter deeper tissues, and a toxic reaction can occur which is sometimes fatal.

It is very important to check your rabbit’s bottom frequently to ensure it is clean and dry. If your rabbit has diarrhea, you will need to wash it to reduce the risk of flystrike.

Rabbits with diarrhea rapidly become dehydrated and need to take in additional fluid to replace those lost. You can encourage your rabbit to drink by offering fresh water in a convenient location. In some cases, fluids can be given via a dropper syringe into the rabbit’s mouth. More severe cases will benefit from veterinary administration of fluids, eg by injections under the skin or via a drip into a vein.

It is important to keep the rabbit’s digestive tract moving. In conditions affecting the tract such as diarrhea, normal motility is often reduced. For this reason, medications called ‘prokinetics’ can be given to stimulate movement in the tract. One of the easiest ways to encourage movement is to give high fiber nutrition. If your rabbit is not eating, you can give a supplement by syringing special high fiber food paste mixes into their mouth.

Rabbits need a high fiber to aid digestion; this stimulates gut motility and also helps wear down the rabbit’s teeth in a natural way. This should be made up of lots of good quality grass hay making up 80% of the rabbit’s diet, 5% good quality extruded nuggets and 15% fresh greens. Such a diet will help reduce the risk of digestive tract disease, including diarrhea.